PEMODELAN SENYAWA PHALERIN BERTANDA 125I UNTUK UJI ANTIRADANG

Wening Lestari, A Mutalib

Abstract


A model of 125I-phalerin was designed in this research. The work was started by designing phalerin based on available data and followed by minimizing energy at bond angles, i.e C4-05-C7-C8 (0 ) , C5-C7-C8-C9 (2),C3-014-C15-C20 (3) and C4-C3-014-C15 (4).This work was then continued with designing of 115l -phalerin. Both models were put in overlaid position, then they were characterized. Result showed that phalerin model has characteristic of bond angle with 1 z 3, 4= 40°, 40°, 320°, 280° respectively. Energy ofphalerin model was 18,7625 kkal/mol. "51-phalern has similarity conformation with phalerin and the RMS for bond length, bond angle 0.0091 a and 0.5039° respectively.

 

 


Keywords


Phalerin, Model of '251-phalerin, Overlay

Full Text:



DOI: http://dx.doi.org/10.14203/widyariset.12.1.2009.127-132

Refbacks

  • There are currently no refbacks.




Copyright (c) 2015 Widyariset

Indexed by :